KIAA1324L
KIAA1324L: A Gene Implicated in Human Health and Disease
Description
KIAA1324L is a gene that encodes a protein called KIAA1324-like protein. This protein is involved in various cellular processes, including cell cycle regulation, DNA repair, and apoptosis (programmed cell death). KIAA1324L is highly expressed in dividing cells, suggesting its crucial role in cell growth and proliferation.
Associated Diseases
Mutations in the KIAA1324L gene have been linked to several human diseases, including:
- Osteosarcoma: A type of bone cancer that primarily affects children and adolescents.
- Ewing sarcoma: A rare type of bone or soft tissue cancer that commonly occurs in children and young adults.
- Small cell carcinoma of the lung: A type of aggressive lung cancer that develops from cells in the airways.
- Thymoma: A tumor of the thymus gland, an organ located in the chest.
- Ovarian clear cell carcinoma: A type of ovarian cancer that affects the cells that produce eggs.
Did you Know ?
Approximately 1 in every 200 cases of osteosarcoma are caused by a mutation in the KIAA1324L gene. This mutation results in the production of an abnormal KIAA1324L protein, which disrupts normal cell growth and survival.
