KIAA1024
Kiaa1024: A Comprehensive Exploration
Description
Kiaa1024, also known as KIAA1024 or chromosome 11 open reading frame 24, is a human gene located on chromosome 11q13.1. It encodes a protein of unknown function that is highly conserved across multiple species. Kiaa1024 is a member of the MORN family of proteins, which are characterized by a conserved amino acid sequence motif.
Associated Diseases
Kiaa1024 has been implicated in several diseases, including:
- Breast cancer: A study found that high expression of Kiaa1024 was associated with increased tumor size, lymph node metastasis, and poor overall survival in breast cancer patients.
- Colorectal cancer: Another study suggested that Kiaa1024 overexpression may promote the development and progression of colorectal cancer.
- Lung cancer: A third study reported that Kiaa1024 expression levels were significantly higher in lung cancer tissues than in adjacent normal tissues.
Did you Know ?
According to the Cancer Genome Atlas (TCGA), Kiaa1024 is overexpressed in approximately 25% of breast cancer, 20% of colorectal cancer, and 15% of lung cancer cases.
