IRX1
Description
The IRX1 (iroquois homeobox 1) is a protein-coding gene located on chromosome 5.
IRX1, a protein encoded by the IRX1 gene in humans, is a member of the Iroquois (IRO) family of homeobox proteins. This family shares common characteristics, including a homeodomain and an IRO sequence motif, and members play crucial roles in early embryonic patterning. IRX1, in particular, acts as a tumor suppressor gene in various cancers. In development, IRX1 is involved in the formation and organization of multiple organs and systems, including lungs, limbs, heart, eyes, and the nervous system. The IRX1 gene is located on chromosome 5, spanning from position 3596054 to 3601403 on the forward strand. The gene encodes a 1858 base pair mRNA with 4 predicted exons.
IRX1 plays a crucial role in the development and patterning of various organs and systems in the human body, including lungs, limbs, heart, eyes, and the nervous system. It acts as a tumor suppressor gene, inhibiting the growth of cancerous cells in several types of cancer.
IRX1 is also known as IRX-5, IRXA1.
