RPS15A


Description

The RPS15A (ribosomal protein S15a) is a protein-coding gene located on chromosome 16.

RPS15A (Ribosomal Protein S15A) is a gene that encodes a protein essential for protein synthesis. It is a component of the small (40S) ribosomal subunit, which is one of the two subunits that make up a ribosome. Ribosomes are responsible for translating genetic information into proteins. RPS15A belongs to the S8P family of ribosomal proteins and is located in the cytoplasm. There are multiple processed pseudogenes of the RPS15A gene dispersed throughout the human genome.

RPS15A, also known as 40S ribosomal protein S15a, is a component of the small ribosomal subunit (40S) involved in protein synthesis. It is a part of the small subunit (SSU) processome, the initial precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, RPS15A collaborates with various ribosome biogenesis factors, an RNA chaperone, and other ribosomal proteins. This complex contributes to RNA folding, modifications, rearrangements, and cleavage. It also participates in the targeted degradation of pre-ribosomal RNA by the RNA exosome. RPS15A is essential for proper erythropoiesis, the process of red blood cell formation.

RPS15A is also known as DBA20, S15a, uS8.

Associated Diseases


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