POLE2

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Description

The POLE2 (DNA polymerase epsilon 2, accessory subunit) is a protein-coding gene located on chromosome 14.

The POLE2 gene in humans encodes for the enzyme DNA polymerase epsilon subunit 2. POLE2 interacts with SAP18.

POLE2 is also known as DPE2.

Associated Diseases

• ovarian cancer
• adult acute lymphoblastic leukemia
• breast cancer
• pancreatic ductal adenocarcinoma
• extranodal nasal NK/T cell lymphoma
• beta-thalassemia major