G6PD

The G6PD gene provides instructions for creating an enzyme called glucose-6-phosphate dehydrogenase. This enzyme plays a critical role in red blood cells, which transport oxygen from the lungs to tissues throughout the body

G6PD Deficiency: Navigating the Challenges of a Common Genetic Condition

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder globally, affecting millions of people. This genetic condition impacts red blood cells‘ ability to cope with oxidative stress, leading to various health challenges.

Understanding G6PD Deficiency: The Basics

G6PD is an essential enzyme that helps protect red blood cells from damage caused by oxidative stress. When G6PD levels are low, red blood cells become vulnerable, leading to their breakdown (hemolysis) and anemia.

G6PD deficiency is inherited in an X-linked recessive pattern, meaning it predominantly affects males, although females can also be carriers or have milder forms of the condition.

Associated Diseases

Glucose-6-Phosphate Dehydrogenase Deficiency

Did you know

According to World Health Organization (WHO) estimation, 7.5% of the world population are carriers of G6PDd and 2.9% are G6PD deficient. G6PD deficiency has been observed ranging from 0% - 30.7% among the different caste, ethnic, and linguistic groups of India.