SNX10
Description
The SNX10 (sorting nexin 10) is a protein-coding gene located on chromosome 7.
SNX10 is a phosphoinositide-binding protein that participates in protein sorting and membrane trafficking within endosomes. It plays a crucial role in cilium biogenesis by regulating the transport and localization of proteins to the cilium. SNX10 is essential for the localization of V-ATPase subunits ATP6V1D and ATP6V0D1, and RAB8A to the cilium. This protein is also involved in osteoclast differentiation, ultimately contributing to bone resorption.
SNX10 is also known as OPTB8.
