RIPK1
Description
The RIPK1 gene encodes a protein kinase known as Receptor Interacting Protein Kinase 1. This protein plays a crucial role in regulating cell death pathways, primarily necroptosis and apoptosis, and is also involved in inflammatory signaling. RIPK1 acts as a signaling hub, interacting with various proteins to initiate or inhibit cell death and inflammation in response to various stimuli, including stress, infection, and DNA damage. Understanding RIPK1‘s function is essential for developing therapeutic strategies targeting inflammatory diseases and cancer.
Associated Diseases
Did you know?
RIPK1 is a ‘double-edged sword‘ - it can promote cell death to eliminate damaged cells, but also contribute to inflammation and disease.
