HELLS
Description
The HELLS gene, also known as Helicase-Like Transcription Factor (HELLS), is a critical component of the cellular machinery responsible for DNA replication and repair. It functions as a DNA helicase, unwinding the double helix to allow access for DNA replication and repair enzymes. This crucial process ensures the integrity of our genetic code, preventing mutations that can lead to diseases like cancer. HELLS plays a role in various cellular processes, including transcription, replication, and recombination. Mutations in the HELLS gene can disrupt these functions, increasing the risk of developing certain cancers. Understanding the role of HELLS in these processes provides valuable insights into cancer development and potential therapeutic targets.
Associated Diseases
- Cancer (various types, including breast, colorectal, and lung cancer)
- DNA repair deficiency disorders
- Developmental disorders
Did you know?
HELLS protein is also known to interact with other DNA repair proteins, forming complex networks that ensure efficient DNA repair and genomic stability.
