HAX1 : HCLS1 associated protein X-1

Description

The HAX1 gene, located on chromosome 11, encodes a protein that plays a vital role in regulating cell growth, survival, and death. It acts as a scaffolding protein, interacting with numerous other proteins to form complexes involved in diverse cellular pathways. HAX1‘s involvement in these processes is crucial for maintaining normal cellular function, and disruptions in its activity can lead to various disease states.

Associated Diseases

• Acute myeloid leukemia (AML)
• Chronic myeloid leukemia (CML)
• Myelodysplastic syndromes (MDS)
• B-cell lymphomas
• Neuroblastoma
• Breast cancer
• Ovarian cancer

Did you know?

Mutations in the HAX1 gene are associated with an increased risk of developing certain cancers, particularly leukemia.