HUS1B
Description
The HUS1B (HUS1 checkpoint clamp component B) is a protein-coding gene located on chromosome 6.
HUS1B is a human gene that encodes a protein involved in DNA damage repair and cell cycle control. It is part of the 9-1-1 checkpoint complex, which is activated in response to DNA damage and stalled replication forks. This complex signals the cell to arrest the cell cycle, allowing time for DNA repair. Mutations in HUS1B have been linked to various genetic disorders, including Fanconi anemia, which is characterized by bone marrow failure and an increased risk of cancer.
HUS1B is also known as -.
