HOXB7
Description
The HOXB7 (homeobox B7) is a protein-coding gene located on chromosome 17.
HOXB7 is a gene that encodes a protein called Homeobox protein Hox-B7. This protein belongs to the Antp homeobox family and has a homeobox DNA-binding domain. It's part of a cluster of homeobox B genes located on chromosome 17. HOXB7 functions as a transcription factor, regulating the activity of other genes. This role is vital in processes like cell proliferation and differentiation. Abnormal HOXB7 expression has been linked to certain cancers, including melanoma and ovarian carcinoma. The protein interacts with PBX1 and CREB-binding protein, suggesting a complex network of interactions in its regulatory function.
HOXB7 is also known as HHO.C1, HOX2, HOX2C, Hox-2.3.
