HOXA5
Description
The HOXA5 (homeobox A5) is a protein-coding gene located on chromosome 7.
HOXA5 is a gene that encodes a protein called homeobox protein Hox-A5. This protein is a transcription factor, a type of protein that controls gene expression. HOXA5 is part of a family of genes called homeobox genes, which are important for development. HOXA5 is involved in regulating gene expression, morphogenesis, and differentiation. It is also important for tumor suppression. HOXA5 expression is regulated by methylation, and its demethylation is associated with endothelial differentiation.
HOXA5 is also known as HOX1, HOX1.3, HOX1C.
Associated Diseases
- glioblastoma
- autosomal recessive spondylocostal dysostosis
- breast cancer
- MHC class I deficiency
- autosomal dominant spondylocostal dysostosis
- spondylometaphyseal dysplasia, A4 type
