HLA-L
Description
The HLA-L (major histocompatibility complex, class I, L (pseudogene)) is a pseudo gene located on chromosome 6.
HLA-L is a non-classical major histocompatibility complex (MHC) class I molecule that is involved in immune regulation. It does not present peptides to T cells like the classical MHC class I molecules (HLA-A, -B, and -C). Instead, HLA-L interacts with immune cells, such as NK cells, and contributes to immune homeostasis, controlling viral infections and tumor development.
HLA-L is a non-classical major histocompatibility complex (MHC) class I molecule. Unlike the classical MHC class I molecules (HLA-A, -B, and -C), HLA-L does not present peptides to T cells. Instead, it plays a role in regulating immune responses and maintaining immune homeostasis. It interacts with various immune cells, including natural killer (NK) cells, and contributes to the control of viral infections and tumor development.
HLA-L is also known as HLA-92, HLA92, HLAL.
Associated Diseases
- cancer
- Wilson disease
- Wolman disease
- cholesteryl ester storage disease
- type 1 diabetes mellitus
- lysosomal storage disease
- central nervous system leukemia
- COVID-19
