RPS7


Description

The RPS7 (ribosomal protein S7) is a protein-coding gene located on chromosome 2.

RPS7 (Ribosomal Protein S7) is a protein encoded by the RPS7 gene in humans. It is a component of the small 40S ribosomal subunit, which, along with the large 60S subunit, comprises the ribosomes that catalyze protein synthesis in eukaryotes. The 40S and 60S subunits are composed of four RNA species and approximately 80 distinct proteins. RPS7 belongs to the S7E family of ribosomal proteins and is located in the cytoplasm. There are multiple processed pseudogenes of the RPS7 gene dispersed throughout the genome.

RPS7, also known as 40S ribosomal protein S7, is a component of the small ribosomal subunit and plays a crucial role in protein synthesis. It is required for rRNA maturation and is part of the small subunit (SSU) processome, the first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, RPS7 interacts with other ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins to facilitate RNA folding, modifications, rearrangements, cleavage, and targeted degradation of pre-ribosomal RNA by the RNA exosome.

RPS7 is also known as DBA8, S7, eS7.

Associated Diseases


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