RPS24 : ribosomal protein S24


Description

The RPS24 (ribosomal protein S24) is a protein-coding gene located on chromosome 10.

The RPS24 gene provides instructions for making a ribosomal protein, one of about 80 different proteins that make up ribosomes. Ribosomes are cellular structures responsible for building proteins from genetic instructions. Ribosomes have two parts: a large and a small subunit. The RPS24 protein is found in the small subunit. The specific functions of RPS24 and other ribosomal proteins are not entirely clear. Some may be involved in ribosome assembly or stability, while others aid in protein synthesis. Research suggests that some ribosomal proteins may have additional roles, such as participating in cell signaling, regulating cell division, and controlling programmed cell death (apoptosis).

RPS24 protein is a component of the small ribosomal subunit, which is crucial for protein synthesis in cells. It is essential for the processing of precursor ribosomal RNA (pre-rRNA) and the maturation of 40S ribosomal subunits. RPS24 is part of the small subunit (SSU) processome, the initial precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, RPS24 interacts with various ribosome biogenesis factors, an RNA chaperone, and other ribosomal proteins to facilitate RNA folding, modifications, rearrangements, and cleavage. This process also involves targeted degradation of pre-ribosomal RNA by the RNA exosome.

RPS24 is also known as DBA3, S24, eS24.

Associated Diseases


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