WRAP53
Description
WRAP53, also known as WW domain-containing adaptor with a coiled-coil (WAC), is a gene that encodes a protein crucial for cellular function. The WRAP53 protein acts as a scaffold, facilitating protein-protein interactions and influencing various cellular pathways, including cell cycle regulation, apoptosis, and DNA damage response. Its intricate involvement in these processes highlights its significance in maintaining cellular homeostasis and preventing disease development.
Associated Diseases
- Cancer: WRAP53 has been implicated in various cancers, including colorectal, breast, and lung cancers. Its dysregulation can contribute to tumor growth and metastasis.
- Neurodegenerative diseases: Studies suggest a potential connection between WRAP53 and neurodegenerative diseases, such as Alzheimer‘s disease and Parkinson‘s disease.
- Cardiovascular diseases: Recent research points to a possible role of WRAP53 in cardiovascular health, particularly in regulating blood vessel formation and heart function.
Did you know?
Interestingly, WRAP53 shares a striking structural similarity with the tumor suppressor protein p53, but its functions are distinct, highlighting the complexity of cellular pathways.
