GCLC
Description
The GCLC gene provides instructions for making the enzyme glutamate-cysteine ligase, a crucial component in the production of glutathione. Glutathione is a powerful antioxidant, protecting cells from damaging free radicals and playing a vital role in detoxification, immune function, and cell signaling. GCLC‘s role in glutathione synthesis makes it a critical gene for maintaining cellular health and protecting against various diseases.
Associated Diseases
- Cancer (various types)
- Neurodegenerative diseases (Alzheimer‘s, Parkinson‘s)
- Liver disease
- Cardiovascular disease
- Inflammatory bowel disease
- Diabetes
- Cataracts
- Asthma
Did you know?
Mutations in the GCLC gene can lead to glutathione deficiency, increasing susceptibility to oxidative stress and disease.
