GRK7


Description

The GRK7 (G protein-coupled receptor kinase 7) is a protein-coding gene located on chromosome 3.

GRK7 (G-protein-coupled receptor kinase 7) is an enzyme that plays a critical role in color vision. It is responsible for phosphorylating cone photopsins, which are proteins responsible for detecting light in the retina. This phosphorylation process helps to regulate the sensitivity of the eye to light, allowing us to see a range of colors. GRK7 is primarily found in retinal cone cells, where it works with other proteins to control the light-activated signaling cascade. GRK7 is a member of the G protein-coupled receptor kinase family, and it is specifically involved in the phosphorylation of light-activated photopsins. These photopsins, which are responsible for recognizing different colors of light, are activated when they absorb light. Once activated, they bind to arrestin-4, a protein that helps to terminate the signaling cascade, preventing the photopsin from continuing to send signals. This process is essential for proper color vision, allowing our eyes to quickly adapt to changes in light intensity and maintain visual clarity.

GRK7 is also known as GPRK7.

Associated Diseases



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