GPR87
Description
The GPR87 (G protein-coupled receptor 87) is a protein-coding gene located on chromosome 3.
GPR87, also known as Probable G-protein coupled receptor 87, is a protein encoded by the GPR87 gene in humans. It is a member of the G protein-coupled receptor family, which plays a key role in cell communication.
GPR87 is a receptor for lysophosphatidic acid (LPA). It plays a crucial role in promoting cell survival in response to DNA damage by activating the p53/TP53 pathway.
GPR87 is also known as FKSG78, GPR95, KPG_002.
Associated Diseases
- diverticulitis
- isolated asymptomatic elevation of creatine phosphokinase
- plasma fibronectin deficiency
- urinary bladder carcinoma
- autosomal recessive spondylocostal dysostosis
- spondyloepiphyseal dysplasia tarda, Kohn type
- spondyloepimetaphyseal dysplasia, Missouri type
- multiple epiphyseal dysplasia
- spondylometaphyseal dysplasia, 'corner fracture' type
- pentosuria