GMFG
The GMFG (Glia Maturation Factor Gamma) gene encodes a protein that belongs to the glia maturation factor family. This protein is involved in various cellular processes, including cell growth, differentiation, and survival. It interacts with actin and is thought to play a role in actin cytoskeleton regulation.
Associated Diseases:
While GMFG‘s exact role in disease development is not fully elucidated, its altered expression has been associated with various conditions, including:
- Cancer: Increased GMFG expression has been observed in several types of cancer, including breast, lung, colorectal, and ovarian cancer. Studies suggest that GMFG may promote tumor growth, invasion, and metastasis.
- Inflammatory Diseases: GMFG has been implicated in inflammatory processes and may contribute to the development of inflammatory diseases.
- Neurological Disorders: Due to its role in glial cell maturation, GMFG dysregulation may be associated with neurological disorders. However, further research is needed to confirm this association.