G0S2
Description
The G0S2 (G0/G1 switch 2) is a protein-coding gene located on chromosome 1.
G0/G1 switch 2 is a protein that in humans is encoded by the G0S2 gene.
G0S2 promotes apoptosis by binding to the BCL2 protein, preventing the formation of protective BCL2-BAX heterodimers. This interaction disrupts the anti-apoptotic function of BCL2, leading to cell death.
G0S2 is also known as -.
Associated Diseases
- cleft palate
- cancer
- achalasia-alacrima syndrome
- obesity due to melanocortin 4 receptor deficiency
- LIPE-related familial partial lipodystrophy
- obesity due to pro-opiomelanocortin deficiency
- obesity due to prohormone convertase I deficiency
- PPARG-related familial partial lipodystrophy
