FUOM
Description
The FUOM (fucose mutarotase) is a protein-coding gene located on chromosome 10.
This enzyme facilitates the conversion of alpha-L-fucose to beta-L-fucose and vice versa. The beta-form of L-fucose, which accounts for the majority of its occurrence, undergoes metabolism through the salvage pathway. GDP-L-fucose, produced either through the de novo or salvage pathways, is then transported to the endoplasmic reticulum. Here, it acts as a substrate for fucosyltransferases, enzymes that attach fucose to proteins and lipids during glycosylation. The resulting fucosylated structures, expressed on cell surfaces or secreted into bodily fluids, are thought to be crucial for cell-cell interactions, including adhesion and recognition.
FUOM is also known as C10orf125, FUCU, FucM.
