FOXJ3
Description
The FOXJ3 (forkhead box J3) is a protein-coding gene located on chromosome 1.
FOXJ3 acts as a transcriptional activator of MEF2C, a protein involved in regulating muscle fiber type identity and muscle regeneration. It also plays a significant role in spermatogenesis, ensuring the survival of spermatogonia and participating in the meiotic division of spermatocytes.
FOXJ3 is also known as -.
Associated Diseases
- familial atrial fibrillation
- Brugada syndrome
- ventricular fibrillation, paroxysmal familial, type 1
- arrhythmogenic right ventricular dysplasia 1
- cardiomyopathy, dilated, 2I
- episodic ataxia type 1
- Brugada syndrome 1
- sinoatrial node dysfunction and deafness
- catecholaminergic polymorphic ventricular tachycardia
- long QT syndrome 5
- spinocerebellar ataxia type 20
