FHL3
Description
The FHL3 (four and a half LIM domains 3) is a protein-coding gene located on chromosome 1.
Four and a half LIM domains protein 3 is a protein that in humans is encoded by the FHL3 gene. LIM proteins are defined by the possession of a highly conserved double zinc finger motif called the LIM domain. FHL3 plays a role in myogenesis, and also stimulates the development of neural crest by enhancing BMP signaling. FHL3 has been shown to interact with CREB1, CTBP2, FHL2, ITGA7, and KLF3.
FHL3 is recruited by SOX15 to FOXK1 promoters, where it acts as a transcriptional coactivator of FOXK1.
FHL3 is also known as SLIM2.
