FGFR1OP
Title: FGFR1OP: A Gene with Intriguing Implications
Description:
FGFR1OP (fibroblast growth factor receptor 1 oncogene partner) is a protein-coding gene that plays a crucial role in various cellular processes, including cell growth, differentiation, and proliferation. Mutations in FGFR1OP have been associated with a range of diseases, from cancer to developmental disorders.
Associated Diseases:
- Cancer: Mutations in FGFR1OP have been linked to several types of cancer, including breast cancer, lung cancer, and glioblastoma. These mutations often lead to increased FGFR1OP activity, promoting uncontrolled cell growth and proliferation.
- Developmental Disorders: FGFR1OP mutations have also been associated with developmental disorders such as Kallmann syndrome and syndromic microcephaly. These disorders are characterized by developmental defects, including impaired growth, intellectual disability, and abnormal facial features.
Did you Know ?
- In a study of breast cancer patients, women with FGFR1OP mutations were found to have a significantly higher risk of developing metastatic disease (spread to other parts of the body) compared to women without FGFR1OP mutations.
