FGD3
Description
The FGD3 (FYVE, RhoGEF and PH domain containing 3) is a protein-coding gene located on chromosome 9.
FGD3, or FYVE, RhoGEF and PH domain-containing protein 3, is a protein encoded by the FGD3 gene in humans.
FGD3 promotes the formation of filopodia, which are finger-like projections that extend from the cell surface. It can activate CDC42, a signaling protein involved in cell growth and movement, by replacing GDP with GTP. This suggests a role for FGD3 in regulating the actin cytoskeleton, the network of protein filaments that gives cells their shape and allows them to move.
FGD3 is also known as ZFYVE5.
