FBXO47
Description
The FBXO47 (F-box protein 47) is a protein-coding gene located on chromosome 17.
FBXO47 likely identifies and attaches to specific proteins that have been modified by the addition of phosphate groups (phosphorylated). This binding triggers a process called ubiquitination, where a small protein tag (ubiquitin) is attached to the target protein. Ubiquitination often signals for the target protein to be broken down by the cell's machinery.
FBXO47 is also known as -.
Associated Diseases
- partial chromosome Y deletion
- male infertility with teratozoospermia due to single gene mutation
- spermatogenic failures 50
- spermatogenic failure 73
- spermatogenic failure 74
- spermatogenic failure 61
- spermatogenic failure 25
- spermatogenic failure, X-linked, 2
- spermatogenic failure 48
- spermatogenic failure 26
- spermatogenic failure 31
- spermatogenic failure 52
- spermatogenic failure 23
- spermatogenic failure 3
- spermatogenic failure 22
- spermatogenic failure 63
- congenital bilateral absence of vas deferens
- spermatogenic failure 29
