FBXO41
Description
The FBXO41 (F-box protein 41) is a protein-coding gene located on chromosome 2.
FBXO41 plays a crucial role in protein degradation by acting as a substrate-recognition component within the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex.
FBXO41 is also known as FBX41.
Associated Diseases
- infantile-onset autosomal recessive nonprogressive cerebellar ataxia
- spinocerebellar ataxia type 35
- spinocerebellar ataxia type 15/16
- spinocerebellar ataxia type 37
- spinocerebellar ataxia type 12
- autosomal recessive spinocerebellar ataxia 17
- spinocerebellar ataxia type 29
- spastic ataxia 2
- spinocerebellar ataxia type 31
- spinocerebellar ataxia type 20
- hereditary spastic paraplegia 30
- autosomal dominant sensory ataxia 1
- spinocerebellar ataxia type 18
