FBXO22-AS1
fbxo22-as1: An Intriguing Long Non-Coding RNA with Diverse Biological Roles
Description:
fbxo22-as1 is a long non-coding RNA (lncRNA) located within the FBXO22 gene on chromosome 16p11.2. LncRNAs are RNA molecules that do not code for proteins but play various regulatory roles in gene expression and cellular processes.
fbxo22-as1 has a complex and multifaceted structure, consisting of multiple exons and introns. Its precise mechanism of action is still being elucidated, but it has been implicated in a wide range of biological functions.
Associated Diseases:
Recent research has linked fbxo22-as1 to several human diseases, including:
- Cancer: Studies have found altered fbxo22-as1 expression in various cancers, such as breast cancer, lung cancer, and colorectal cancer. It appears to play a role in tumorigenesis, metastasis, and drug resistance.
- Cardiovascular disease: fbxo22-as1 has been associated with the development of atherosclerosis and heart failure. It may contribute to endothelial dysfunction, inflammation, and plaque formation.
- Neurological disorders: Aberrant fbxo22-as1 expression has been observed in Alzheimer's disease and Parkinson's disease. It may be involved in neuronal damage and neuroinflammation.
Did you Know ?
- A study examining fbxo22-as1 expression in breast cancer patients found that high levels of the lncRNA were significantly associated with worse overall survival and disease-free survival rates.
