FAM76A


Description

The FAM76A (family with sequence similarity 76 member A) is a protein-coding gene located on chromosome 1.

FAM76A is a protein encoded by the FAM76A gene in humans. It's characterized by an 83 amino acid coiled coil domain and a poly-serine bias. FAM76A is conserved in most chordates but not in other deuterostomes like echinoderms, hemichordates, or xenacoelomorphs, suggesting it emerged after chordates in the evolutionary lineage. It's also absent in fungi, plants, archaea, and bacteria. FAM76A is predicted to localize to the nucleus and may play a role in regulating transcription.

Gene

Location

FAM76A is located on the (+) strand of the short arm of chromosome 1 (1p35.3), with the genomic sequence spanning from 27725979 to 27762915. The coding region comprises 3462 base pairs and translates into 341 amino acids.

Gene neighborhood

Genes flanking FAM76A on the telomeric side include IFI6, CHMP1AP1, and RPEP3, while genes flanking it on the centromeric side include STX12, PPP1R8, and L0C105376894.

Common aliases

In Caenorhabditis elegans, FAM76A is referred to as K04F10.7. Outside of this, it has no significant alternative names.

FAM76A is also known as -.

Associated Diseases



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