FAM35DP
Family with Sequence Similarity 35 Member D (FAM35D)
Description
FAM35D is a gene that encodes a protein involved in various cellular processes, including DNA repair, cell cycle regulation, and apoptosis. It is located on chromosome 19p13.3 and consists of 11 exons spanning approximately 104 kilobases.
Associated Diseases
Mutations in the FAM35D gene have been associated with several diseases, including:
- Fanconi Anemia: A rare genetic disorder characterized by bone marrow failure, developmental abnormalities, and an increased risk of certain types of cancer.
- Myelodysplastic Syndrome: A condition in which the bone marrow fails to produce healthy blood cells.
- Acute Myeloid Leukemia: A type of blood cancer that originates in the myeloid cells of the bone marrow.
Did you Know ?
- Mutations in the FAM35D gene account for approximately 5-10% of Fanconi Anemia cases.
