FAM214B
Title: FAM214B: A Gene with Far-Reaching Implications in Alzheimer's Disease and Cancer
Description:
FAM214B is a gene that encodes a protein called family with sequence similarity 214 member B. This protein is involved in various cellular processes, including DNA repair, cell cycle regulation, and apoptosis. FAM214B has been linked to several diseases, including Alzheimer's disease and cancer.
Associated Diseases:
Alzheimer's Disease:
- FAM214B is a risk factor for Alzheimer's disease, a neurodegenerative disorder that affects memory, thinking, and behavior.
- Studies have found that people with certain variations in the FAM214B gene have an increased risk of developing Alzheimer's disease.
- The FAM214B protein is thought to play a role in the formation of amyloid plaques, which are protein deposits that accumulate in the brains of people with Alzheimer's disease.
Cancer:
- FAM214B has also been implicated in the development of various types of cancer, including breast cancer, lung cancer, and colorectal cancer.
- Alterations in FAM214B expression or function can disrupt cell cycle regulation and promote cancer cell growth.
- The FAM214B protein is involved in DNA damage repair, and defects in this process can lead to genomic instability and cancer development.
Did you Know ?
- In a study of over 2,000 individuals, researchers found that people with a specific variation in the FAM214B gene had a 30% increased risk of developing Alzheimer's disease compared to those without the variation.
