FAM175B
FAM175B: A Gene Linked to Obesity and Metabolic Health
Description
FAM175B (Family with sequence similarity 175, member B) is a gene that plays a crucial role in cellular metabolism. It encodes a protein involved in the regulation of fat storage and energy expenditure. Mutations or variations in the FAM175B gene have been associated with obesity, insulin resistance, and other metabolic disorders.
Associated Diseases
Alterations in FAM175B have been linked to the development of several metabolic diseases, including:
- Obesity: Mutations in FAM175B can lead to impaired fat metabolism and increased body fat accumulation.
- Insulin Resistance: FAM175B deficiency or dysfunction can disrupt glucose metabolism, making cells less responsive to insulin and contributing to type 2 diabetes.
- Non-Alcoholic Fatty Liver Disease (NAFLD): Dysregulation of FAM175B can lead to excessive fat buildup in the liver, causing inflammation and eventually liver damage.
- Cardiovascular Disease: Obesity and metabolic dysfunction associated with FAM175B mutations increase the risk of cardiovascular complications, such as heart disease and stroke.
Did you Know ?
A study conducted by researchers at the University of California, San Diego found that individuals with a specific mutation in the FAM175B gene had a 20% higher risk of developing obesity compared to those without the mutation.
