FAM167A
Description
The FAM167A (family with sequence similarity 167 member A) is a protein-coding gene located on chromosome 8.
FAM167A, or Family with sequence similarity 167, member A, is a protein in humans encoded by the FAM167A gene located on chromosome 8. FAM167A and its paralogs contain the conserved domain DUF3259, a protein of unknown function. FAM167A has many orthologs in which the domain of unknown function is highly conserved.
== Gene ==
=== Locus === On chromosome 8, FAM167A is positioned between c8orf12 (anti-sense) and BLK (anti-sense). The exact locus of FAM167A is 8p23-22 and spans from 11,278,972 to 11,332,224, a total of 53,253 base pairs. The promoter spans from 11324145 to 11324476 on the negative strand, thereby the first basepair is actually on 11324476. There are no human isoforms found.
=== Aliases === Family with Sequence Similarity 167, Member A is also known as FAM167A, c8orf13, or D8S265.
== Homology ==
=== Paralogs === FAM167A has one paralog, FAM167B also known as c1orf90. FAM167B is located at 1p35.1 on the plus strand and is composed of 163 amino acids and also contains DUF3259.
The function of FAM167A protein is currently unknown. It contains a conserved domain called DUF3259, which is found in other proteins with unknown functions. This domain is highly conserved across different species, suggesting its potential importance.
FAM167A is also known as C8orf13, D8S265, DIORA-1.
