FAM151A
Description
The FAM151A (family with sequence similarity 151 member A) is a protein-coding gene located on chromosome 1.
FAM151A is a human gene located on chromosome 1. It encodes a transmembrane protein expressed in the kidney tubules. The protein is an ortholog of menorin, a protein involved in neuron development in nematodes. The gene contains 8 exons and spans approximately 14 kbp. The mRNA transcript is expressed in the kidney, small intestine, and liver. The protein is only expressed in kidney tubules. It has three known domains, including one transmembrane domain and two DUF2181 domains, which are members of the GDPD/PLCD superfamily and are known to hydrolyze glycerophosphodiester bonds. The second DUF2181 is hypothesized to be nonfunctional.
FAM151A is a transmembrane protein expressed in the kidney tubules. It is an ortholog of menorin, a protein involved in neuron development in nematodes. FAM151A has three known domains: one transmembrane domain and two domains of unknown function (DUF2181). DUF2181 is a member of the GDPD/PLCD superfamily, which are known to hydrolyze glycerophosphodiester bonds. The second DUF2181 of FAM151A is hypothesized to be nonfunctional through homology analysis.
FAM151A is also known as C1orf179.
