FAM13B
Description
The FAM13B (family with sequence similarity 13 member B) is a protein-coding gene located on chromosome 5.
The FAM13B gene, also known as C5ORF5, encodes a protein called Family with sequence similarity 13 member B. This gene is found in vertebrates and jawed fish. FAM13B is expressed in many human tissues and has been linked to malignant myelomas susceptibility and atrial fibrillation, a heart rhythm problem.
Molecular Features
- Gene: The FAM13B gene is located on chromosome 5, spanning 5610 base pairs with 23 exons.
- mRNA: There are 18 different mRNA transcripts, with the longest one being 5610 base pairs long.
- Expression: FAM13B is expressed in various human tissues, with the highest levels in the brain and the lowest in the liver.
- Protein: The largest FAM13B protein contains 915 amino acids and has a molecular weight of 105 kDa. The protein can be modified in various ways, resulting in different forms with deletions or changes in its structure. It has an isoelectric point of 4.9 and is found in the nucleus. It contains signals that direct it to the nucleus and peroxisomes. The FAM13B protein has less threonine and more glutamate than average human proteins.
FAM13B is also known as ARHGAP49, C5orf5, FAM13B1, KHCHP, N61.
