FAM114A2
Description
The FAM114A2 (family with sequence similarity 114 member A2) is a protein-coding gene located on chromosome 5.
FAM114A2 (chromosome 5 open reading frame 3) is a gene on chromosome 5 in humans that encodes a protein FAM114A2. The protein function is not well known. FAM114A2 is, however, highly conserved in mammals with homologs both in fungi and plants.
== Protein == The FAM114A2 protein is 505 amino acids long with a molecular weight of 55.5 kdal and an isoelectric point of 4.66. It is predicted to stay in the nucleus after translation There is evidence that c5orf3 interacts with another protein of unknown function from chromosome 5, c5orf4 This protein is thought to include a P loop that suggests a role in ATP- and/or GTP-binding
== Gene == The FAM114A2 gene is located on chromosome 5 (5q31-33). This gene has 14 exons spanning through its sequence. The coding sequence is 2886 base pairs with a 5’ UTR of 94 base pairs and a 3’ UTR of 1273 base pairs. It is expressed at high levels in most tissues of the human body. It is also highly expressed in tissues in the human brain
== References ==
== External links == Human FAM114A2 genome location and FAM114A2 gene details page in the UCSC Genome Browser.
FAM114A2, also known as chromosome 5 open reading frame 3 (C5ORF3), is a gene located on chromosome 5 in humans. Its encoded protein, FAM114A2, is highly conserved across mammals and has homologs in fungi and plants, suggesting an important but yet undefined function. The protein is predicted to reside in the nucleus after translation and may interact with another protein of unknown function, C5ORF4, also located on chromosome 5. The presence of a P loop within the protein suggests potential involvement in ATP- or GTP-binding.
FAM114A2 is also known as 133K02, C5orf3.
