FAM114A1
Description
The FAM114A1 (family with sequence similarity 114 member A1) is a protein-coding gene located on chromosome 4.
Protein FAM114A1, also known as nervous system overexpressed protein 20 (NOXP20), is a protein encoded by the FAM114A1 gene in humans. Orthologs of FAM114A1 are found in organisms as diverse as Drosophila. However, human FAM114A1 is more closely related to those of primates. FAM114A1 has one paralog, FAM114A2, which also encodes a protein of unknown function.
FAM114A1 is located on the short arm of Chromosome 4 (4.p14) in humans on the forward strand sense, starting at base pair 38869354 and ending at 38947365. Its mRNA has 4138 bp. The gene has the following neighbors on the same chromosome:
- TLR1: Toll-like receptor (TLR) 1 plays a role in pathogen recognition and activation of innate immunity.
- TLR6: Toll-like receptor (TLR) 6 plays a role in pathogen recognition and activation of innate immunity.
- TMEM156: The gene codes for a transmembrane protein.
FAM114A1 is also known as Noxp20.
