FAM104A
FAM104A: A Gene Associated with Multiple Cancers and Diseases
Description
FAM104A (family with sequence similarity 104, member A) is a gene that encodes a protein with various functions in DNA repair, cell cycle regulation, and apoptosis. It is located on chromosome 1p36.13.
Associated Diseases
FAM104A mutations have been linked to several diseases, including:
1. Cancers:
- Breast cancer
- Ovarian cancer
- Colon cancer
- Lung cancer
2. Hematological disorders:
- Chronic lymphocytic leukemia
- Acute myeloid leukemia
- Myelodysplastic syndromes
3. Neurodegenerative disorders:
- Alzheimer's disease
- Parkinson's disease
- Amyotrophic lateral sclerosis (ALS)
4. Other diseases:
- Autism spectrum disorder
- Type 2 diabetes
- Obesity
Did you Know ?
- A study published in Nature Genetics found that mutations in FAM104A were present in approximately 5% of breast cancer patients.
