F3
Description
The F3 (coagulation factor III, tissue factor) is a protein-coding gene located on chromosome 1.
F3 or F03 may refer to:
F3, or Tissue Factor (TF), initiates blood clotting by forming a complex with circulating factor VII or VIIa. This complex activates factors IX or X through limited proteolysis. TF is essential for normal hemostasis, initiating the assembly and propagation of the coagulation protease cascade on the cell surface.
F3 is also known as CD142, TF, TFA.
Associated Diseases
- cervical cancer
- peritoneum cancer
- ovarian cancer
- fallopian tube cancer
- retinitis pigmentosa
- lung cancer
- cancer
- BAP1-related tumor predisposition syndrome
- platelet-type von Willebrand disease
- Leber congenital amaurosis
- colorectal cancer, susceptibility to, 12
- Glanzmann thrombasthenia 1
- familial atypical multiple mole melanoma syndrome
