EXOC7
Description
The EXOC7 (exocyst complex component 7) is a protein-coding gene located on chromosome 17.
EXOC7, also known as Exo70, is a protein encoded by the EXOC7 gene in humans. It is a subunit of the exocyst complex, a protein complex involved in exocytosis, the process of releasing molecules from cells. The exocyst complex was first discovered in yeast, where it plays a crucial role in the final stages of exocytosis by helping vesicles fuse with the plasma membrane. In humans, the exact functions of EXOC7 and the exocyst complex are not fully understood, but it is believed to be involved in exocytosis and is expressed in various tissues. EXOC7 interacts with the Rho3 GTPase, a protein that regulates cell polarity, and is involved in vesicle docking and fusion with the plasma membrane.
EXOC7 is a component of the exocyst complex, which plays a key role in docking exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, EXOC7 is essential for targeting SLC2A4 vesicles to the plasma membrane in response to insulin, possibly guiding the vesicle to its specific fusion site. Additionally, EXOC7 is crucial for neuron survival and plays a vital role in cortical development.
EXOC7 is also known as 2-5-3p, BLOM4, EX070, EXO70, EXOC1, Exo70p, NEDSEBA, YJL085W.
