EXOC5
Description
The EXOC5 (exocyst complex component 5) is a protein-coding gene located on chromosome 14.
Exocyst complex component 5 is a protein that in humans is encoded by the EXOC5 gene. The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. EXOC5 has been shown to interact with Arf6.
EXOC5 is also known as HSEC10, PRO1912, SEC10, SEC10L1, SEC10P.
