EXOC4
Description
The EXOC4 (exocyst complex component 4) is a protein-coding gene located on chromosome 7.
EXOC4 (Exocyst complex component 4) is a protein encoded by the EXOC4 gene in humans. It is a key component of the exocyst complex, a multi-protein structure that is essential for guiding exocytic vesicles (tiny sacs containing cellular cargo) to their specific docking sites on the cell's outer membrane (plasma membrane). The exocyst complex is highly conserved across different organisms, and its function in regulating vesicle trafficking is vital for cell growth, communication, and overall function. This protein, along with other exocyst complex components, interacts with elements involved in reorganizing the actin cytoskeleton, a crucial structural framework within cells. The exocyst complex is also essential for establishing the proper organization and polarity of epithelial cells, which line many surfaces in the body. The EXOC4 gene can generate different versions of the protein (isoforms) through alternative splicing, which may have distinct functions.
EXOC4 is a component of the exocyst complex, which plays a crucial role in guiding exocytic vesicles to their specific docking sites on the cell's outer membrane (plasma membrane).
EXOC4 is also known as SEC8, SEC8L1, Sec8p.
Associated Diseases
- Meckel syndrome
- Parkinson disease
- multiple sclerosis
- Alzheimer disease
- lysosomal storage disease
- endometrial cancer
