DPYD-AS1
Description
The DPYD-AS1 (DPYD antisense RNA 1) is a ncRNA gene located on chromosome 1.
DPYD-AS1 is a long non-coding RNA (lncRNA) gene located on chromosome 1p36.13. It is involved in the regulation of dihydropyrimidine dehydrogenase (DPYD) expression, which is an enzyme that plays a crucial role in the metabolism of 5-fluorouracil (5-FU), a commonly used chemotherapy drug. Studies suggest that DPYD-AS1 may act as a tumor suppressor by inhibiting DPYD expression and thereby reducing 5-FU metabolism, leading to increased sensitivity to the drug. Further research is needed to fully elucidate its precise role in cancer development and response to treatment.
DPYD-AS1 is a long non-coding RNA (lncRNA) that is located on chromosome 1p36.13. It has been shown to be involved in the regulation of dihydropyrimidine dehydrogenase (DPYD) expression, which is an enzyme that plays a role in the metabolism of 5-fluorouracil (5-FU), a chemotherapy drug. Studies have indicated that DPYD-AS1 may act as a tumor suppressor by inhibiting DPYD expression and thus reducing 5-FU metabolism, leading to increased sensitivity to the drug. However, further research is needed to fully understand its role in cancer development and response to therapy.
DPYD-AS1 is also known as -.
