DNAJC27

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Description

The DNAJC27 (DnaJ heat shock protein family (Hsp40) member C27) is a protein-coding gene located on chromosome 2.

DNAJC27 is a GTPase that can activate the MEK/ERK pathway and induce cell transformation when overexpressed. It may act as a nuclear scaffold for MAPK1, potentially by interacting with its nuclear export signal, leading to increased ERK1/ERK2 signaling.

DNAJC27 is also known as RBJ, RabJS.

Associated Diseases