DMXL1
Description
The DMXL1 (Dmx like 1) is a protein-coding gene located on chromosome 5.
DMXL1, also known as Deleted in Malignant Brain Tumors 1, is a protein-coding gene located on human chromosome 17. It encodes a protein involved in the process of mitosis, the division of a cell into two daughter cells. DMXL1 is essential for proper chromosome segregation during mitosis, ensuring that each daughter cell receives the correct number of chromosomes. The protein interacts with various components of the mitotic spindle, the structure that separates chromosomes during cell division, and plays a crucial role in regulating microtubule dynamics. Mutations or dysregulation of DMXL1 have been implicated in various human diseases, including cancer and developmental disorders.
DMXL1 plays a critical role in cell division, particularly during the separation of chromosomes. It acts as a scaffolding protein, linking together various components of the mitotic spindle, ensuring proper chromosome alignment and segregation. This protein is essential for maintaining the integrity of the genome and preventing aneuploidy, a condition where cells have an abnormal number of chromosomes. Additionally, DMXL1 is involved in the regulation of microtubule dynamics, which are essential for cell motility and intracellular transport. Disruptions in DMXL1 function have been linked to developmental defects and tumorigenesis.
DMXL1 is also known as -.
