DIO3OS
Description
The DIO3OS (DIO3 opposite strand upstream RNA) is a ncRNA gene located on chromosome 14.
DIO3OS (Deiodinase, Iodothyronine, Type III) is a gene that encodes a protein that is thought to play a role in the regulation of thyroid hormone metabolism.
The DIO3OS gene encodes a protein that is thought to play a role in the regulation of thyroid hormone metabolism. The protein is a type 3 iodothyronine deiodinase (DIO3), which is an enzyme that catalyzes the removal of iodine from thyroid hormones. This activity results in the inactivation of thyroid hormones. DIO3 is expressed in a variety of tissues, including the brain, pituitary gland, liver, and kidney. Its expression is regulated by a number of factors, including thyroid hormone itself, growth hormone, and glucocorticoids.
DIO3OS is also known as C14orf134, DIO3-AS1, DIO3-OS, NCRNA00041.