SNRPE
Description
The SNRPE (small nuclear ribonucleoprotein polypeptide E) is a protein-coding gene located on chromosome 1.
Small nuclear ribonucleoprotein E is a protein that in humans is encoded by the SNRPE gene.
SNRPE plays a crucial role in pre-mRNA splicing. It is a core component of the spliceosomal U1, U2, U4, and U5 small nuclear ribonucleoproteins (snRNPs), which are essential building blocks of the spliceosome. SNRPE is involved in both the pre-catalytic spliceosome B complex and the activated spliceosome C complexes. It is also a component of the minor spliceosome, participating in the splicing of U12-type introns in pre-mRNAs. Additionally, SNRPE is part of the U7 snRNP, where it contributes to histone 3'-end processing.
SNRPE is also known as HYPT11, SME, Sm-E, snRNP-E.
