SLC27A4

Description

SLC27A4, also known as the fatty acid transporter protein 4 (FATP4), plays a crucial role in the uptake and transport of long-chain fatty acids (LCFAs) across cell membranes. It is primarily expressed in tissues with high lipid metabolism activity, including the liver, adipose tissue, and skeletal muscle. SLC27A4 facilitates the entry of LCFAs into cells, where they can be used for energy production, lipid synthesis, or other metabolic processes. Its function is essential for maintaining normal lipid homeostasis and energy balance in the body.

Associated Diseases

• Nonalcoholic fatty liver disease (NAFLD)
• Obesity
• Insulin resistance
• Type 2 diabetes
• Cardiovascular disease
• Cancer

Did you know?

Mutations in the SLC27A4 gene can lead to rare inherited disorders characterized by impaired fatty acid metabolism and lipid accumulation in various tissues.